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October 31, 2022

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Mbagwu experiences being an worker of Verana Well being.

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Earlier than the 2022 American Academy of Ophthalmology assembly, Verana Well being, the expertise, information and analytics associate for the Academy’s IRIS Registry, shared its 2021 IRIS Registry Trade Report.

Among the many highlights of the report are the massive quantity of cumulative information out there within the IRIS Registry — information managed by Verana Well being’s VeraQ information engine — by way of the tip of 2021. In all, the report displays greater than 434 million billable visits with 72 million sufferers, together with 5.6 million sufferers with non-exudative age-related macular degeneration, 1.5 million with diabetic macular edema, 10.6 million with cataract, 15.5 million with totally different types of myopia and 14 million with glaucoma. Most significantly, we’ve got as much as 9 years of follow-up information out there now, making it potential to raised perceive the impression of ailments and surgical and medical interventions over time.

IRIS image 1200x600
Variety of sufferers who obtained a specific glaucoma process between Jan. 1, 2013, and Dec. 31, 2021, by yr. Supply: 2021 IRIS Registry Trade Report

Analysis highlights

For instance, the non-exudative AMD information had been just lately used within the largest burden-of-disease retrospective examine of geographic atrophy (GA). Researchers adopted 69,000 sufferers over 2 years, offering insights into the speed of development from extrafoveal to foveal GA. Researchers had been additionally in a position to make use of IRIS Registry information to make clear variations and similarities in outcomes and charges of endophthalmitis amongst sufferers present process fast vs. delayed sequential bilateral cataract surgical procedure. Summaries of those research, together with 13 others using IRIS Registry information that had been printed in 2021, are included within the report.

Glaucoma insights

The report additionally takes a deep dive into information on developments in glaucoma surgical procedure from 2013 to 2021 within the IRIS Registry. Throughout this 8-year interval, glaucoma process quantity climbed steadily, however the sorts of process modified significantly (Determine 1). Trabeculectomies, for instance, peaked in 2015, with 14,600 procedures per yr, then started to say no. By 2021, there have been simply 9,300 trabeculectomies yearly, regardless of rising charges of glaucoma within the inhabitants. Over the identical interval, there was a dramatic enhance in minimally invasive glaucoma surgical procedure procedures, together with the implantation of trabecular meshwork micro-bypass stents. Inside a yr of the approval of a dual-stent implant, the variety of eyes receiving a second stent climbed from just some dozen per yr earlier than approval to greater than 20,000 per yr prior to now 3 years.

Because of advances in glaucoma surgical strategies and gadgets, procedures akin to MIGS can now happen earlier within the illness course, slowing down or stabilizing glaucomatous development. However as glaucoma surgical choices proceed to develop, the IRIS Registry is usually a highly effective supply of longitudinal information to assist reply questions on optimum patterns of care.

Verana Well being

The 2021 IRIS Registry Trade Report additionally particulars the methods through which Verana Well being is curating information from its VeraQ inhabitants well being information engine to create high-quality Qdata modules. The primary such module in ophthalmology, Qdata Glaucoma, is already getting used to assist discover patient-reported outcomes with MIGS within the PRO-MIGS examine, performed in partnership with the Academy, the FDA, the Heart of Excellence in Regulatory Science and Innovation at UCSF-Stanford and the American Glaucoma Society. Qdata modules for anti-VEGF injections and different remedies and subspecialty areas inside ophthalmology, together with inherited retinal illness, neovascular and non-neovascular AMD, diabetic macular edema, cataract and extra, are underneath growth.

I’m excited concerning the continued effort to collect and analyze significant information on how sufferers expertise care. Because the IRIS Registry continues to develop by way of its supplier footprint and linked information sources through VeraQ — together with medical claims, pharmacy claims and diagnostic photographs — the chance to advance medical analysis and affected person outcomes is immense.

The complete report is obtainable at


  • Khan MA, et al. Make investments Ophthalmol Vis Sci. 2021;62:166.
  • Lacy M, et al. Ophthalmology. 2022;doi:10.1016/j.ophtha.2021.07.008.

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